Posted 20 hours ago

Nuromol Pain Relief Tablets, Paracetamol and Ibuprofen, Pack Of 16, From The Makers Of Nurofen

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Antenatal monitoring for oligohydramnios and ductus arteriosus constriction should be considered after exposure to Nuromol Dual Action for several days from gestational week 20 onward. NSAIDs should not be used during the first two trimesters of pregnancy or labour unless the potential benefit to the patient outweighs the potential risk to the foetus.

g. hypertension, hyperlipidaemia, diabetes mellitus, smoking) particularly if high doses of ibuprofen (2400 mg/day) are required. The first is 500mg of paracetamol, an everyday painkiller that can also help to bring down a fever or high temperature. Other NSAIDs including cyclo-oxygenase-2 selective inhibitors as these may increase the risk of adverse effects (see Section 4. Ibuprofen therefore elicits an analgesic effect through peripheral inhibition of the cycloxygenase-2 (COX-2) isoenzyme with a subsequent reduction in sensitisation of nociceptive nerve terminals.

Prolonged use at higher than recommended doses may result in severe hypokalaemia and renal tubular acidosis. Since Nuromol is already classified as a Pharmacy Medicine, the MHRA considered the application against the General Sales criterion. Do not use until first trying ibuprofen or paracetamol individually to relieve your pain according to the pack instructions.

NSAIDs should be given with care to patients with a history of GI disease (ulcerative colitis, Crohn's disease) as these conditions may be exacerbated (see Section 4. In patients with severe hepatic failure, severe renal failure or severe heart failure (NYHA Class IV) (see Section 4. In addition, consideration was given to the following issues: The risk that a person may confuse the product with paracetamol alone and take the standard paracetamol dose of 2 tablets four times a day. g. misoprostol or proton pump inhibitors) should be considered for these patients, and also for patients requiring concomitant low dose acetylsalicylic acid, or other drugs likely to increase gastrointestinal risk (see below and 4.

Ibuprofen is well absorbed from the gastrointestinal tract and is extensively bound to plasma proteins. This has been observed in bacterial community acquired pneumonia and bacterial complications to varicella. Paracetamol's exact mechanism of action is still not completely defined; however there is considerable evidence to support the hypothesis of a central antinociceptive effect. There is limited evidence that drugs which inhibit cyclo-oxygenase/prostaglandin synthesis may impair female fertility by an effect on ovulation and is not recommended in women attempting to conceive.

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